Aplnr^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Aplnr^tm1Dgen
• Name: apelin receptor; targeted mutation 1, Deltagen
• MGI ID: MGI:5433631
• Gene: Aplnr Location: Chr2:84966704-84970267 bp, + strand Genetic Position: Chr2, 49.45 cM, cytoband E1
• Alliance: Aplnr^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186909
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• Mutation details: In situ hybridization histochemistry confirmed the absence of protein expression in peripheral tissues from homozygous mice. (J:186909)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aplnr Mutation: 30 strains or lines available

References

• Original: J:186909 Roberts EM, et al., Abnormal fluid homeostasis in apelin receptor knockout mice. J Endocrinol. 2009 Sep;202(3):453-62
• All: 4 reference(s)