Tg(Csf1r-cre/Esr1*)1Jwp
Transgene Detail

Summary

• Symbol: Tg(Csf1r-cre/Esr1*)1Jwp
• Name: transgene insertion 1, Jeffrey W Pollard
• MGI ID: MGI:5433683
• Synonyms: tg(Csf1r-Mer-iCre-Mer)1Jwp
• Transgene: Tg(Csf1r-cre/Esr1*)1Jwp Location: unknown
• Alliance: Tg(Csf1r-cre/Esr1*)1Jwp page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Csf1r-cre/Esr1*)1Jwp expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Csf1r

• Mutation details: A transgene construct was generated in which the Csf1r promoter was used to drive expression of icre fused to 2 tamoxifen-inducible mutated estrogen receptors (Mer-icre-Mer or icre/Esr1*). Line 1 was used in the primary reference. (J:186831)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Csf1r (species not specified) Summary of all recombinase alleles driven by Csf1r. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:186831 Qian BZ, et al., CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature. 2011 Jul 14;475(7355):222-5
• All: 71 reference(s)