Galnt3^tcal
Chemically induced Allele Detail

Summary

• Symbol: Galnt3^tcal
• Name: polypeptide N-acetylgalactosaminyltransferase 3; Familial Tumoural Calcinosis
• MGI ID: MGI:5435287
• Synonyms: Pebbles, Tcal
• Gene: Galnt3 Location: Chr2:65913110-65955217 bp, - strand Genetic Position: Chr2, 38.99 cM, cytoband C3
• Alliance: Galnt3^tcal page

Ectopic calcifications, testicular abnormalities, and increased apoptosis in Galnt3^tcal/Galnt3^tcal mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: These mice were identified in an ENU screen. DNA sequence analysis identified a Galnt3 missense mutation (Trp589Arg). (J:187064)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Galnt3 Mutation: 29 strains or lines available

References

• Original: J:187064 Esapa CT, et al., A Mouse with an N-Ethyl-N-Nitrosourea (ENU) Induced Trp589Arg Galnt3 Mutation Represents a Model for Hyperphosphataemic Familial Tumoural Calcinosis. PLoS One. 2012;7(8):e43205
• All: 1 reference(s)