Dpf2^tm1.2Grc
Targeted Allele Detail

Summary

• Symbol: Dpf2^tm1.2Grc
• Name: double PHD fingers 2; targeted mutation 1.2, Gerald R Crabtree
• MGI ID: MGI:5435603
• Synonyms: Baf45d^F/F
• Gene: Dpf2 Location: Chr19:5946544-5962899 bp, - strand Genetic Position: Chr19, 4.34 cM
• Alliance: Dpf2^tm1.2Grc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP-flanked neomycin resistance cassette with TK promoter was introduced into intron 3. Transient Cre expression removed the Neo cassette, leaving a residual intron 3 loxP site. The ES cells were re-targeted to introduce a loxP-flanked neomycin cassette into intron 1. Transient Cre expression excised this neo cassette, leaving exons 2 and 3 flanked by loxP sites. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dpf2 Mutation: 38 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)