Kit^M1Hmgu
Chemically induced Allele Detail

Summary

• Symbol: Kit^M1Hmgu
• Name: KIT proto-oncogene receptor tyrosine kinase; mutation 1, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5436087
• Synonyms: Kit^N824K, MVD013
• Gene: Kit Location: Chr5:75735647-75817382 bp, + strand Genetic Position: Chr5, 39.55 cM
• Alliance: Kit^M1Hmgu page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a point mutation that results in the amino acid substitution of asparagine with lysine at position 824 (p.N824K). (J:327874)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kit Mutation: 182 strains or lines available

References

• Original: J:186868 Aigner B, et al., Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters. Mamm Genome. 2011 Oct;22(9-10):495-505
• All: 2 reference(s)