Rasl10b^tm1Eno
Targeted Allele Detail

Summary

• Symbol: Rasl10b^tm1Eno
• Name: RAS-like, family 10, member B; targeted mutation 1, Eric N Olson
• MGI ID: MGI:5437949
• Synonyms: RRP17^-
• Gene: Rasl10b Location: Chr11:83299963-83311865 bp, + strand Genetic Position: Chr11, 50.3 cM
• Alliance: Rasl10b^tm1Eno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187574
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ-neomycin cassette replaced the coding region of the gene contained in exons 2, 3, and part of exon 4. RT-PCR analysis demonstrated the complete absence of transcripts in homozygotes. (J:187574)

Expression

In Mice Carrying this Mutation:

15 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasl10b Mutation: 16 strains or lines available

References

• Original: J:187574 Rybkin II, et al., Regulation of atrial natriuretic peptide secretion by a novel Ras-like protein. J Cell Biol. 2007 Nov 5;179(3):527-37
• All: 1 reference(s)