Sh2d1b1^tm3Vei
Targeted Allele Detail

Summary

• Symbol: Sh2d1b1^tm3Vei
• Name: SH2 domain containing 1B1; targeted mutation 3, Andre Veillette
• MGI ID: MGI:5438032
• Gene: Sh2d1b1 Location: Chr1:170104889-170114338 bp, + strand Genetic Position: Chr1, 76.84 cM, cytoband H2
• Alliance: Sh2d1b1^tm3Vei page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187430
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• No details provided

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sh2d1b1 Mutation: 11 strains or lines available

References

• Original: J:187430 Dong Z, et al., The adaptor SAP controls NK cell activation by regulating the enzymes Vav-1 and SHIP-1 and by enhancing conjugates with target cells. Immunity. 2012 Jun 29;36(6):974-85
• All: 2 reference(s)