Rnf212^tm1Nhtr
Targeted Allele Detail

Summary

• Symbol: Rnf212^tm1Nhtr
• Name: ring finger protein 212; targeted mutation 1, Neil Hunter
• MGI ID: MGI:5438282
• Gene: Rnf212 Location: Chr5:108877156-108922848 bp, - strand Genetic Position: Chr5, 53.24 cM
• Alliance: Rnf212^tm1Nhtr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187173
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaces promoter and first two exons. Western blot analysis confirmed the absence of protein in the testes. (J:94077, J:196206)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rnf212 Mutation: 11 strains or lines available

References

• Original: J:187173 Qiao H, et al., Interplay between synaptonemal complex, homologous recombination, and centromeres during mammalian meiosis. PLoS Genet. 2012 Jun;8(6):e1002790
• All: 7 reference(s)