Plk3^tm1Elan
Targeted Allele Detail

Summary

• Symbol: Plk3^tm1Elan
• Name: polo like kinase 3; targeted mutation 1, Elan Pharmaceuticals Inc
• MGI ID: MGI:5438531
• Gene: Plk3 Location: Chr4:116985852-116991160 bp, - strand Genetic Position: Chr4, 53.41 cM
• Alliance: Plk3^tm1Elan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:201467
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A targeting construct contained a FRT site flanked NEO cassette. (J:201467)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Plk3 Mutation: 34 strains or lines available

References

• Original: J:201467 Bergeron M, et al., In vivo modulation of polo-like kinases supports a key role for PLK2 in Ser129 alpha-synuclein phosphorylation in mouse brain. Neuroscience. 2014 Jan 3;256:72-82
• All: 1 reference(s)