Alpl^ALPLD1
Chemically induced Allele Detail

Summary

• Symbol: Alpl^ALPLD1
• Name: alkaline phosphatase, liver/bone/kidney; alkaline phosphatase low level dominant 1
• MGI ID: MGI:5438641
• Synonyms: ALP-01
• Gene: Alpl Location: Chr4:137469044-137523695 bp, - strand Genetic Position: Chr4, 70.02 cM
• Alliance: Alpl^ALPLD1 page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis resulted in an A to G transition at nucleotide position 326 of exon5. This caused an aspartic acid to glycine change in codon 109. (J:187875)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Alpl Mutation: 352 strains or lines available

References

• Original: J:68708 Hrabe de Angelis MH, et al., Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet. 2000 Aug;25(4):444-7
• All: 2 reference(s)