Usp46^{Gt(pU17)1Imeg}
Gene trapped Allele Detail

Summary

• Symbol: Usp46^{Gt(pU17)1Imeg}
• Name: ubiquitin specific peptidase 46; gene trap 1, Institute of Molecular Embryology and Genetics
• MGI ID: MGI:5438668
• Gene: Usp46 Location: Chr5:74159387-74229070 bp, - strand Genetic Position: Chr5, 39.33 cM
• Alliance: Usp46^{Gt(pU17)1Imeg} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187828
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (C57BL/6 x CBA)F1

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The pU17 gene trap vector (floxed beta-geo cassette, polyadenylation sequence, lox2272 site, pSP73 vector and lox511 site) inserted into intron 1. Western blot analysis confirmed the absence of protein expression in the brain. (J:110088, J:187828)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp46 Mutation: 79 strains or lines available

References

• Original: J:187828 Imai S, et al., Ubiquitin-specific peptidase 46 (Usp46) regulates mouse immobile behavior in the tail suspension test through the GABAergic system. PLoS One. 2012;7(6):e39084
• All: 3 reference(s)