Fgf22^tm1Rpgr
Targeted Allele Detail

Summary

• Symbol: Fgf22^tm1Rpgr
• Name: fibroblast growth factor 22; targeted mutation 1, Richard P Grose
• MGI ID: MGI:5438777
• Gene: Fgf22 Location: Chr10:79590887-79593629 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Fgf22^tm1Rpgr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187809
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: The coding regions in exons 1, 2 and 3 were replaced with a neo cassette. RT-PCR confirmed the absence of transcript expression in the brain. (J:187809)

Generation of the Fgf22^tm1Rpgr allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf22 Mutation: 15 strains or lines available

References

• Original: J:187809 Jarosz M, et al., Fibroblast growth factor 22 is not essential for skin development and repair but plays a role in tumorigenesis. PLoS One. 2012;7(6):e39436
• All: 1 reference(s)