Gt(ROSA)26Sor^{tm1(LDLR/avidin)Svo}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(LDLR/avidin)Svo}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Seppo Vainio
• MGI ID: MGI:5438799
• Synonyms: Rosa26Lodavin
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(LDLR/avidin)Svo} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187859
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A loxP followed by a PGK-betageo construct, three SV40 polyA sites, and a second loxP site was inserted in the Gt(ROSA)26Sor locus followed by a fused human low density lipoprotein receptor/avidin sequence. (J:187859)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:187859 Murugan S, et al., Conditional expression of Lodavin, an avidin-tagged LDL receptor, for biotin-mediated applications in vivo. Genesis. 2012 Sep;50(9):693-9
• All: 1 reference(s)