Ccl17^{tm2.1(cre)Ifo}
Targeted Allele Detail

Summary

• Symbol: Ccl17^{tm2.1(cre)Ifo}
• Name: C-C motif chemokine ligand 17; targeted mutation 2.1, Irmgard Foerster
• MGI ID: MGI:5438830
• Synonyms: CCl17Cre
• Gene: Ccl17 Location: Chr8:95537081-95538664 bp, + strand Genetic Position: Chr8, 46.85 cM
• Alliance: Ccl17^{tm2.1(cre)Ifo} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187773
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Ccl17^{tm2.1(cre)Ifo} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ccl17 (MGI:1329039)

• Mutation details: A targeting construct was generated with cDNA encoding cre recombinase with nuclear localization signal and an Frt-flanked neomycin selection cassette. Homologous recombination in E14.1 ES cells inserted the cre and neo selection marker into the second exon of Ccl17. Flp expression in vitro deleted the neomycin cassette. (J:187773)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ccl17 (mouse) Summary of all recombinase alleles driven by Ccl17. Alliance mouse Ccl17 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccl17 Mutation: 11 strains or lines available

References

• Original: J:187773 Kohler T, et al., Influence of hypoxia-inducible factor 1alpha on dendritic cell differentiation and migration. Eur J Immunol. 2012 May;42(5):1226-36
• All: 1 reference(s)