Havcr1^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Havcr1^tm1Vlcg
• Name: hepatitis A virus cellular receptor 1; targeted mutation 1, Velocigene
• MGI ID: MGI:5438833
• Gene: Havcr1 Location: Chr11:46630644-46670405 bp, + strand Genetic Position: Chr11, 28.08 cM
• Alliance: Havcr1^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187793
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: LacZ replaced exon 4 and 5. FACS analysis confirmed the absence of protein expression in CD19+ gated cells. (J:187793)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Havcr1 Mutation: 29 strains or lines available

References

• Original: J:187793 Curtiss ML, et al., Tim-1 regulates Th2 responses in an airway hypersensitivity model. Eur J Immunol. 2012 Mar;42(3):651-61
• All: 2 reference(s)