Lrpprc^tm1.2Lrsn
Targeted Allele Detail

Summary

• Symbol: Lrpprc^tm1.2Lrsn
• Name: leucine-rich PPR-motif containing; targeted mutation 1.2, Nils-Goran Larsson
• MGI ID: MGI:5438913
• Gene: Lrpprc Location: Chr17:85012675-85098214 bp, - strand Genetic Position: Chr17, 55.02 cM
• Alliance: Lrpprc^tm1.2Lrsn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187800
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination of Lrpprc^tm1.1Lrsn removed exons 3 through 5. (J:187800)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrpprc Mutation: 60 strains or lines available

References

• Original: J:187800 Ruzzenente B, et al., LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs. EMBO J. 2012 Jan 18;31(2):443-56
• All: 1 reference(s)