Gem^tm1Jgun
Targeted Allele Detail

Summary

• Symbol: Gem^tm1Jgun
• Name: GTP binding protein overexpressed in skeletal muscle; targeted mutation 1, Jenny E Gunton
• MGI ID: MGI:5439007
• Synonyms: Gem^flox
• Gene: Gem Location: Chr4:11704457-11714752 bp, + strand Genetic Position: Chr4, 5.34 cM
• Alliance: Gem^tm1Jgun page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187922
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Exon 2 was floxed. (J:187922)

Schematic of the Gem^tm1Jgun and Gem^tm1.1Jgun alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gem Mutation: 15 strains or lines available

References

• Original: J:187922 Gunton JE, et al., Mice deficient in GEM GTPase show abnormal glucose homeostasis due to defects in beta-cell calcium handling. PLoS One. 2012;7(6):e39462
• All: 1 reference(s)