Gpr37l1^tm1.1Gtva
Targeted Allele Detail

Summary

• Symbol: Gpr37l1^tm1.1Gtva
• Name: G protein-coupled receptor 37-like 1; targeted mutation 1.1, Glauco Tocchini-Valentini
• MGI ID: MGI:5439168
• Synonyms: Gpr37l1^flox
• Gene: Gpr37l1 Location: Chr1:135087988-135095419 bp, - strand Genetic Position: Chr1, 58.25 cM
• Alliance: Gpr37l1^tm1.1Gtva page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:201190
• Parent Cell Line: XSV1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A single loxP site was inserted upstream of exon 1 and a floxed neomycin resistance cassette was inserted in intron 1. Cre-mediated recombination removed the neo cassette and left exon 1 floxed. (J:201190)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr37l1 Mutation: 33 strains or lines available

References

• Original: J:201190 Marazziti D, et al., Precocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptor. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16486-16491
• All: 1 reference(s)