Tg(Prrxl1-cre/ERT2)1Yqd
Transgene Detail

Summary

• Symbol: Tg(Prrxl1-cre/ERT2)1Yqd
• Name: transgene insertion 1, Yu-Qiang Ding
• MGI ID: MGI:5439541
• Synonyms: Prrxl1-CreER^T2
• Transgene: Tg(Prrxl1-cre/ERT2)1Yqd Location: unknown
• Alliance: Tg(Prrxl1-cre/ERT2)1Yqd page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Prrxl1-cre/ERT2)1Yqd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Drgx (MGI:2148204)

• Mutation details: DNA encoding the cre/ERT2 open reading frame, a bovine growth hormone (BGH) polyA tag, and an frt-flanked kanamycin selection cassette was inserted into the first exon of the Prrxl1 gene in BAC clone RP23-199P8 by homologous recombination in EL250 bacterial cells. Flp expression was induced to excise the kanamycin cassette. The purified BAC construct was injected into FVB/N fertilized eggs. Founder information is not available. (J:187485)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Drgx (mouse) Summary of all recombinase alleles driven by Drgx. Alliance mouse Drgx gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:187485 Hu ZL, et al., Inducible Prrxl1-CreER(T2) recombination activity in the somatosensory afferent pathway. Genesis. 2012 Jul;50(7):552-60
• All: 5 reference(s)