Ubl4a^tm1.1Xya
Targeted Allele Detail

Summary

• Symbol: Ubl4a^tm1.1Xya
• Name: ubiquitin-like 4A; targeted mutation 1.1, Xiao Yang
• MGI ID: MGI:5439599
• Synonyms: GdX^-
• Gene: Ubl4a Location: ChrX:73409324-73412154 bp, - strand Genetic Position: ChrX, 38.0 cM
• Alliance: Ubl4a^tm1.1Xya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187502
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed exon 2 and the neo cassette. Western blot analysis confirmed the absence of protein expression in the heart, liver, lung, spleen, brain, kidney, intestine, colon, stomach and testis. (J:187502)

Generation of the Ubl4a^tm1Xya and Ubl4a^tm1.1Xya alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ubl4a Mutation: 4 strains or lines available

References

• Original: J:187502 Wang Y, et al., Generation of mice with conditional null allele for GdX/Ubl4A. Genesis. 2012 Jul;50(7):534-42
• All: 6 reference(s)