Syndig1l^tm1Embr
Targeted Allele Detail

Summary

• Symbol: Syndig1l^tm1Embr
• Name: synapse differentiation inducing 1 like; targeted mutation 1, Emmanuel Brouillet
• MGI ID: MGI:5440443
• Synonyms: Capucin knockout
• Gene: Syndig1l Location: Chr12:84724051-84745605 bp, - strand Genetic Position: Chr12, 39.33 cM
• Alliance: Syndig1l^tm1Embr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188308
• Parent Cell Line: AT1 (ES Cell)
• Strain of Origin: 129S2/SvPasCrl

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding sequence was replaced with a beta-galactosidase, neomycin selection cassette. Northern blot analysis confirmed the absence of transcript. (J:188308)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Syndig1l Mutation: 14 strains or lines available

References

• Original: J:188308 Galvan L, et al., Capucin does not modify the toxicity of a mutant Huntingtin fragment in vivo. Neurobiol Aging. 2012 Aug;33(8):1845.e5-6
• All: 1 reference(s)