Tg(Myh6-Fhod3*I1127A)#Hsum
Transgene Detail

Summary

• Symbol: Tg(Myh6-Fhod3*I1127A)#Hsum
• Name: transgene insertion, Hideki Sumimoto
• MGI ID: MGI:5440647
• Synonyms: Fhod3^{Tg(alpha-MHC-Fhod3IA)}
• Transgene: Tg(Myh6-Fhod3*I1127A)#Hsum Location: unknown
• Alliance: Tg(Myh6-Fhod3*I1127A)#Hsum page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Fhod3*I1127A)#Hsum expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fhod3 (MGI:1925847)

• Mutation details: The promoter drives cardiac expression of a modified cDNA in which nucleotide substitution resulted in the amino acid substitution of alanine for isoleucine at position 1127 (I1127A). The pound symbol (#) is used when no line is psecified and/or lines are pooled. (J:187358)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:187358 Kan-o M, et al., Mammalian formin Fhod3 plays an essential role in cardiogenesis by organizing myofibrillogenesis. Biol Open. 2012;1(9):889-896
• All: 1 reference(s)