Map3k12tm1.1Adia
Targeted Allele Detail
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Symbol: |
Map3k12tm1.1Adia |
Name: |
mitogen-activated protein kinase kinase kinase 12; targeted mutation 1.1, Aaron DiAntonio |
MGI ID: |
MGI:5440722 |
Synonyms: |
DLKlox |
Gene: |
Map3k12 Location: Chr15:102406079-102425311 bp, - strand Genetic Position: Chr15, 57.63 cM, cytoband F3
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Alliance: |
Map3k12tm1.1Adia page
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Germline Transmission: |
Earliest citation of germline transmission:
J:188476
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6J
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: An FRT-flanked neo cassette with a 5' loxP cassette was inserted upstream of exon 8. An additional loxP site was inserted downstream of exon 11. Flp-mediated recombination removed the neo cassette and left exons 8 through 11 floxed. These exons code the kinase domain.
(J:188476)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Map3k12 Mutation: |
39 strains or lines available
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Original: |
J:188476 Miller BR, et al., A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration. Nat Neurosci. 2009 Apr;12(4):387-9 |
All: |
9 reference(s) |
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