Fstl1^tm1Nju
Targeted Allele Detail

Summary

• Symbol: Fstl1^tm1Nju
• Name: follistatin-like 1; targeted mutation 1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:5440890
• Gene: Fstl1 Location: Chr16:37597417-37656878 bp, + strand Genetic Position: Chr16, 26.48 cM
• Alliance: Fstl1^tm1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188549
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 2 via homologous recombination. (J:188549)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fstl1 Mutation: 46 strains or lines available

References

• Original: J:188549 Li KC, et al., Follistatin-like 1 suppresses sensory afferent transmission by activating Na+,K+-ATPase. Neuron. 2011 Mar 10;69(5):974-87
• All: 5 reference(s)