Fstl1^tm1.1Nju
Targeted Allele Detail

Summary

• Symbol: Fstl1^tm1.1Nju
• Name: follistatin-like 1; targeted mutation 1.1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:5440894
• Gene: Fstl1 Location: Chr16:37597417-37656878 bp, + strand Genetic Position: Chr16, 26.48 cM
• Alliance: Fstl1^tm1.1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187117
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 2 via homologous recombination. Cre mediated recombination removed the neo cassette and exon 2. (J:188549)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fstl1 Mutation: 46 strains or lines available

References

• Original: J:187117 Xu J, et al., Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554
• All: 4 reference(s)