Gsk3btm2138.1Arte
Targeted Allele Detail
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Symbol: |
Gsk3btm2138.1Arte |
Name: |
glycogen synthase kinase 3 beta; targeted mutation 2138.1, TaconicArtemis |
MGI ID: |
MGI:5440976 |
Synonyms: |
GSK3betaASKA, GSK3betatm2138(V110I,L132A,F175L)Arte, Gsk3btm1Arte |
Gene: |
Gsk3b Location: Chr16:37909363-38066446 bp, + strand Genetic Position: Chr16, 26.54 cM, cytoband B4
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Alliance: |
Gsk3btm2138.1Arte page
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Germline Transmission: |
Earliest citation of germline transmission:
J:188272
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6NTac
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Allele Type: |
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Targeted |
Mutations: |
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Insertion, Nucleotide substitutions
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Mutation details: Nucleotide substitutions result in the amino acid sibstitution of isoleucine to valine at position 110 (V110I), alanine for leucine at position 132 (L132A) and leucine for phenylalanine at position 175 (F175L). Flp-mediated recombination removed the FRT-flanked neo cassette.
(J:188272)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gsk3b Mutation: |
113 strains or lines available
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Original: |
J:188272 Chen M, et al., Spatially coordinated kinase signaling regulates local axon degeneration. J Neurosci. 2012 Sep 26;32(39):13439-53 |
All: |
2 reference(s) |
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