Med23^tm1Berk
Targeted Allele Detail

Summary

• Symbol: Med23^tm1Berk
• Name: mediator complex subunit 23; targeted mutation 1, Arnold J Berk
• MGI ID: MGI:5441005
• Gene: Med23 Location: Chr10:24745889-24789358 bp, + strand Genetic Position: Chr10, Syntenic
• Alliance: Med23^tm1Berk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188551
• Parent Cell Line: LW1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced part of exon 2 and all of exons 3 and 4 resulting in a 125 amino acid deletion. (J:125417)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Med23 Mutation: 75 strains or lines available

References

• Original: J:125417 Stevens JL, et al., Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit. Science. 2002 Apr 26;296(5568):755-8
• All: 4 reference(s)