About   Help   FAQ
Ddit3tm2.1Dron
Targeted Allele Detail
Summary
Symbol: Ddit3tm2.1Dron
Name: DNA-damage inducible transcript 3; targeted mutation 2.1, David Ron
MGI ID: MGI:5441015
Synonyms: Chop-, CHOP::LacZ
Gene: Ddit3  Location: Chr10:127126662-127132160 bp, + strand  Genetic Position: Chr10, 74.5 cM
Alliance: Ddit3tm2.1Dron page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA NLS-lacZ cassette and a floxed PGK-Neo cassette replaced the coding region in parts of exons 3 and 4. Cre-mediated recombination removed the neo cassette. (J:101977)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 6 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ddit3 Mutation:  20 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  86 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory