Mis18a^tm1.2Kiik
Targeted Allele Detail

Summary

• Symbol: Mis18a^tm1.2Kiik
• Name: MIS18 kinetochore protein A; targeted mutation 1.2, Keun Il Kim
• MGI ID: MGI:5441069
• Synonyms: Mis18a^delta
• Gene: Mis18a Location: Chr16:90516200-90524259 bp, - strand Genetic Position: Chr16, 51.87 cM, cytoband C3.3
• Alliance: Mis18a^tm1.2Kiik page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188023
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination of Mis18a^tm1.1Kiik removed exons 1 and 2. (J:188023)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mis18a Mutation: 13 strains or lines available

References

• Original: J:188023 Kim IS, et al., Roles of Mis18alpha in epigenetic regulation of centromeric chromatin and CENP-A loading. Mol Cell. 2012 May 11;46(3):260-73
• All: 2 reference(s)