Tg(Igkv3-5-MYC)#Plbe
Transgene Detail

Summary

• Symbol: Tg(Igkv3-5-MYC)#Plbe
• Name: transgene insertion, P Leif Bergsagel
• MGI ID: MGI:5441309
• Synonyms: Vk-MYC
• Transgene: Tg(Igkv3-5-MYC)#Plbe Location: unknown
• Alliance: Tg(Igkv3-5-MYC)#Plbe page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Igkv3-5-MYC)#Plbe expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MYC (4609)

  Bmyc	(MGI:88184)
  Myc	(MGI:97250)

• Mutation details: The mouse promoter drives B cell-specific expression of the human MYC coding sequence (exons 2 and 3; Genbank vector MN894515 without stop codon). Lines 3 and 20 were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:99667)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:99667 Robbiani DF, et al., Maintained rules of development in a mouse B-cell tumor. Leukemia. 2005 Jul;19(7):1278-80
• All: 4 reference(s)