Tg(Pkd1)248Som
Transgene Detail

Summary

• Symbol: Tg(Pkd1)248Som
• Name: transgene insertion 248, Stefan Somlo
• MGI ID: MGI:5442173
• Synonyms: Pkd1^F/H-BAC, Tg(RPCI22-287A3)248Som
• Transgene: Tg(Pkd1)248Som Location: unknown
• Alliance: Tg(Pkd1)248Som page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL/J)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pkd1)248Som expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pkd1 (MGI:97603)

• Mutation details: The transgene was generated from a modified BAC RPCI22-287A3 in which three copies of an HA tag were inserted downstream of the stop codon and three copies of the FLAG tag was inserted after the leader sequence. Line 248 contains three copies of the transgene. (J:188763)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:188763 Fedeles SV, et al., A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation. Nat Genet. 2011 Jul;43(7):639-47
• All: 4 reference(s)