Prkcsh^tm1.1Som
Targeted Allele Detail

Summary

• Symbol: Prkcsh^tm1.1Som
• Name: protein kinase C substrate 80K-H; targeted mutation 1.1, Stefan Somlo
• MGI ID: MGI:5442302
• Gene: Prkcsh Location: Chr9:21914314-21925521 bp, + strand Genetic Position: Chr9, 8.04 cM
• Alliance: Prkcsh^tm1.1Som page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188763
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exons 6 and 7. (J:188763)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkcsh Mutation: 27 strains or lines available

References

• Original: J:188763 Fedeles SV, et al., A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation. Nat Genet. 2011 Jul;43(7):639-47
• All: 1 reference(s)