Rgs16^tm1.1Drue
Targeted Allele Detail

Summary

• Symbol: Rgs16^tm1.1Drue
• Name: regulator of G-protein signaling 16; targeted mutation 1.1, Kirk M Druey
• MGI ID: MGI:5442790
• Gene: Rgs16 Location: Chr1:153616099-153621212 bp, + strand Genetic Position: Chr1, 65.43 cM
• Alliance: Rgs16^tm1.1Drue page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188966
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Cre-mediated recombination removed exons 2 through 4 and the neo cassette. (J:188966)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rgs16 Mutation: 21 strains or lines available

References

• Original: J:188966 Shankar SP, et al., RGS16 attenuates pulmonary Th2/Th17 inflammatory responses. J Immunol. 2012 Jun 15;188(12):6347-56
• All: 4 reference(s)