Spns2^{tm1c(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Spns2^{tm1c(KOMP)Wtsi}
• Name: SPNS lysolipid transporter 2, sphingosine-1-phosphate; targeted mutation 1c, Wellcome Trust Sanger Institute
• MGI ID: MGI:5442806
• Synonyms: Spns2^f
• Gene: Spns2 Location: Chr11:72342464-72380730 bp, - strand Genetic Position: Chr11, 44.31 cM
• Alliance: Spns2^{tm1c(KOMP)Wtsi} page
• IMPC: Spns2 gene page

Mutation origin

• Mutant Cell Line: EPD0090_5_B04
• Germline Transmission: Earliest citation of germline transmission: J:188933
• Parent Cell Line: JM8.N19 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: Flp-mediated recombination removed the reporter construct and selection cassette and left exon 3 floxed. (J:188933)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spns2 Mutation: 31 strains or lines available

References

• Original: J:188933 Nijnik A, et al., The role of sphingosine-1-phosphate transporter Spns2 in immune system function. J Immunol. 2012 Jul 1;189(1):102-11
• All: 11 reference(s)