Tg(Myh6-Trp53*R193P)3Ljf
Transgene Detail

Summary

• Symbol: Tg(Myh6-Trp53*R193P)3Ljf
• Name: transgene insertion 3, Loren J Field
• MGI ID: MGI:5443852
• Synonyms: MHC-CB7
• Transgene: Tg(Myh6-Trp53*R193P)3Ljf Location: unknown
• Alliance: Tg(Myh6-Trp53*R193P)3Ljf page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Dominant negative, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Trp53*R193P)3Ljf expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Trp53 (MGI:98834)

• Mutation details: The mouse promoter drives cardiomyocyte-specific expression of a section of the murine genomic clone with a dominant negative mutation (R193P; clone CB7). Five lines were generated, including line 3. (J:135392)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:135392 Nakajima H, et al., Expression of mutant p193 and p53 permits cardiomyocyte cell cycle reentry after myocardial infarction in transgenic mice. Circ Res. 2004 Jun 25;94(12):1606-14
• All: 3 reference(s)