Cd109^tm1Mat
Targeted Allele Detail

Summary

• Symbol: Cd109^tm1Mat
• Name: CD109 antigen; targeted mutation 1, Masahide Takahashi
• MGI ID: MGI:5443927
• Gene: Cd109 Location: Chr9:78522828-78623535 bp, + strand Genetic Position: Chr9, 43.65 cM
• Alliance: Cd109^tm1Mat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188696
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 1 and all of exon 2 were replaced with lacZ and pgk-neo cassettes via homologous recombination. Western blot analysis confirmed the absence of protein expression in lysates from skin and testes of homozygous mice. (J:188696)

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cd109 Mutation: 103 strains or lines available

References

• Original: J:188696 Mii S, et al., Epidermal Hyperplasia and Appendage Abnormalities in Mice Lacking CD109. Am J Pathol. 2012 Oct;181(4):1180-9
• All: 7 reference(s)