Nat8l^tm1Atni
Targeted Allele Detail

Summary

• Symbol: Nat8l^tm1Atni
• Name: N-acetyltransferase 8-like; targeted mutation 1, Atsumi Nitta
• MGI ID: MGI:5444021
• Gene: Nat8l Location: Chr5:34153328-34163260 bp, + strand Genetic Position: Chr5, 17.83 cM
• Alliance: Nat8l^tm1Atni page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188917
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: All 3 exons were replaced with a neo cassette via homologous recombination. Real time RT-PCR confirmed the absence of RNA expression in brains from homozygous mice. (J:188917)

Expression

In Mice Carrying this Mutation:

18 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nat8l Mutation: 15 strains or lines available

References

• Original: J:188917 Furukawa-Hibi Y, et al., Absence of SHATI/Nat8l reduces social interaction in mice. Neurosci Lett. 2012 Sep 27;526(2):79-84
• All: 7 reference(s)