Gucy1b2^tm3Mom
Targeted Allele Detail

Summary

• Symbol: Gucy1b2^tm3Mom
• Name: guanylate cyclase 1, soluble, beta 2; targeted mutation 3, Peter Mombaerts
• MGI ID: MGI:5444155
• Synonyms: Gucy1b2-GFP, Gucy1b2-IRES-tauGFP
• Gene: Gucy1b2 Location: Chr14:62630125-62693738 bp, - strand Genetic Position: Chr14, 33.21 cM
• Alliance: Gucy1b2^tm3Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:218085
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES-tauGFP-ACNF casette was inserted after the stop codon resulting in bicistronic expression of the endogenous protein and the tauGFP marker. (J:218085)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gucy1b2 Mutation: 33 strains or lines available

References

• Original: J:218085 Omura M, et al., Trpc2-expressing sensory neurons in the mouse main olfactory epithelium of type B express the soluble guanylate cyclase Gucy1b2. Mol Cell Neurosci. 2015 Mar;65:114-24
• All: 4 reference(s)