Irx3^tm3.1Hui
Targeted Allele Detail

Summary

• Symbol: Irx3^tm3.1Hui
• Name: Iroquois related homeobox 3; targeted mutation 3.1, Chi-Chung Hui
• MGI ID: MGI:5444473
• Synonyms: Irx3^KO
• Gene: Irx3 Location: Chr8:92525139-92528282 bp, - strand Genetic Position: Chr8, 44.55 cM
• Alliance: Irx3^tm3.1Hui page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189007
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 to 4 were floxed via homologous recombination. Cre mediated recombination removed exons 2 to 4. (J:189007)

Expression

In Mice Carrying this Mutation:

47 assay results 3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Irx3 Mutation: 25 strains or lines available

References

• Original: J:189007 Gaborit N, et al., Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology. Development. 2012 Nov;139(21):4007-19
• All: 5 reference(s)