Tcf7l2^tm1Geno
Targeted Allele Detail

Summary

• Symbol: Tcf7l2^tm1Geno
• Name: transcription factor 7 like 2, T cell specific, HMG box; targeted mutation 1, Genoway
• MGI ID: MGI:5444885
• Synonyms: Tcf7l2-flox
• Gene: Tcf7l2 Location: Chr19:55730252-55922086 bp, + strand Genetic Position: Chr19, 51.59 cM
• Alliance: Tcf7l2^tm1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189204
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 1 was floxed. (J:189204)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcf7l2 Mutation: 58 strains or lines available

References

• Original: J:189204 da Silva Xavier G, et al., Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice. Diabetologia. 2012 Oct;55(10):2667-76
• All: 5 reference(s)