Fnip1^tm1.2Baba
Targeted Allele Detail

Summary

• Symbol: Fnip1^tm1.2Baba
• Name: folliculin interacting protein 1; targeted mutation 1.2, Masaya Baba
• MGI ID: MGI:5445116
• Synonyms: Fnip1^d
• Gene: Fnip1 Location: Chr11:54329025-54409061 bp, + strand Genetic Position: Chr11, 32.13 cM
• Alliance: Fnip1^tm1.2Baba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189078
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neo cassette with a loxP site was inserted upstream of exon 6. An additional loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the neo cassette and left exon 6 floxed. Cre-mediated recombination removed exon 6. (J:189078)

Disease models

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fnip1 Mutation: 60 strains or lines available

References

• Original: J:189078 Baba M, et al., The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dube syndrome is required for murine B-cell development. Blood. 2012 Aug 9;120(6):1254-61
• All: 2 reference(s)