Klra15^tm1.1Apma
Targeted Allele Detail

Summary

• Symbol: Klra15^tm1.1Apma
• Name: killer cell lectin-like receptor, subfamily A, member 15; targeted mutation 1.1, Andrew P Makrigiannis
• MGI ID: MGI:5445244
• Synonyms: NKC^KD
• Gene: Klra15 Location: unknown Genetic Position: Chr6, cytoband F3
• Alliance: Klra15^tm1.1Apma page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189106
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: The promoter region was targeted with a floxed neo cassette. Cre-mediated recombination removed the neo cassette. The targeting vector unexpectedly inserted as a concatemer. (J:189106)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klra15 Mutation: 0 strains or lines available

Notes

This allele was originally generated in ES cells conataining Klra17^tm1Apma.

References

• Original: J:189106 Belanger S, et al., Impaired natural killer cell self-education and "missing-self" responses in Ly49-deficient mice. Blood. 2012 Jul 19;120(3):592-602
• All: 4 reference(s)