Ccdc80^tm1Ftrm
Targeted Allele Detail

Summary

• Symbol: Ccdc80^tm1Ftrm
• Name: coiled-coil domain containing 80; targeted mutation 1, Frederic Tremblay
• MGI ID: MGI:5445519
• Gene: Ccdc80 Location: Chr16:44913770-44948287 bp, + strand Genetic Position: Chr16, 29.39 cM, cytoband B5
• Alliance: Ccdc80^tm1Ftrm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189183
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exon 1 and 2. The absence of transcript expression in white adipose tissue was confirmed. (J:189183)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccdc80 Mutation: 52 strains or lines available

References

• Original: J:189183 Tremblay F, et al., Loss of coiled-coil domain containing 80 negatively modulates glucose homeostasis in diet-induced obese mice. Endocrinology. 2012 Sep;153(9):4290-303
• All: 1 reference(s)