Slc2a8^tm1Khm
Targeted Allele Detail

Summary

• Symbol: Slc2a8^tm1Khm
• Name: solute carrier family 2, (facilitated glucose transporter), member 8; targeted mutation 1, Kelle H Moley
• MGI ID: MGI:5445581
• Gene: Slc2a8 Location: Chr2:32863002-32872095 bp, - strand Genetic Position: Chr2, 22.09 cM
• Alliance: Slc2a8^tm1Khm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189148
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exons 1 through 4. RT-PCR confirmed the absence of trancsript expression in the testes, heart and liver. (J:192418)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc2a8 Mutation: 19 strains or lines available

References

• Original: J:189148 DeBosch BJ, et al., Glucose transporter 8 (GLUT8) regulates enterocyte fructose transport and global mammalian fructose utilization. Endocrinology. 2012 Sep;153(9):4181-91
• All: 5 reference(s)