Cdx2^tm1.2Aral
Targeted Allele Detail

Summary

• Symbol: Cdx2^tm1.2Aral
• Name: caudal type homeobox 2; targeted mutation 1.2, Amy Ralston
• MGI ID: MGI:5445745
• Synonyms: Cdx2^del
• Gene: Cdx2 Location: Chr5:147237710-147244059 bp, - strand Genetic Position: Chr5, 86.86 cM, cytoband G2-G3
• Alliance: Cdx2^tm1.2Aral page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189005
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1 and a loxP site and FRT flanked inverted neo cassette were inserted downstream of exon 1 via homologous recombination. Flp mediated recombination removed the neo cassette. Cre mediated recombination removed exon 1. (J:189005)

Expression

In Mice Carrying this Mutation:

5 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdx2 Mutation: 22 strains or lines available

References

• Original: J:189005 Blij S, et al., Maternal Cdx2 is dispensable for mouse development. Development. 2012 Nov;139(21):3969-72
• All: 1 reference(s)