Ghsr^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Ghsr^{tm1.1(KOMP)Vlcg}
• Name: growth hormone secretagogue receptor; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5445806
• Gene: Ghsr Location: Chr3:27425500-27432159 bp, + strand Genetic Position: Chr3, 10.86 cM
• Alliance: Ghsr^{tm1.1(KOMP)Vlcg} page
• IMPC: Ghsr gene page

Mutation origin

• Mutant Cell Line: 12455A-G6
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 3150bp between positions 27270722-27273871 of Chromosome 3 (Genome Build37) and subsequent cre expression excised the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:

23 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ghsr Mutation: 27 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 9 reference(s)