Capn1^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Capn1^tm1.1Arte
• Name: calpain 1; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:5445809
• Synonyms: mu-cal^fl
• Gene: Capn1 Location: Chr19:6038573-6065855 bp, - strand Genetic Position: Chr19, 4.34 cM
• Alliance: Capn1^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189100
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites and FRT and F3 flanked positive selection cassettes were inserted flanking exons 5 - 8. Flp mediated recombination removed the selection cassettes leaving exons 5 - 8 floxed. (J:189100)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Capn1 Mutation: 33 strains or lines available

References

• Original: J:189100 Randriamboavonjy V, et al., Calpain inhibition stabilizes the platelet proteome and reactivity in diabetes. Blood. 2012 Jul 12;120(2):415-23
• All: 2 reference(s)