Kcnh3^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Kcnh3^{tm1.1(KOMP)Vlcg}
• Name: potassium voltage-gated channel, subfamily H (eag-related), member 3; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5445933
• Gene: Kcnh3 Location: Chr15:99122742-99140698 bp, + strand Genetic Position: Chr15, 56.08 cM, cytoband F3
• Alliance: Kcnh3^{tm1.1(KOMP)Vlcg} page
• IMPC: Kcnh3 gene page

Mutation origin

• Mutant Cell Line: 17146A-A5
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 17563bp between positions 99055410-99072972 of Chromosome 15 (Genome Build37) and subsequent cre expression excised the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:	11 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kcnh3 Mutation: 42 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 6 reference(s)