Setd6tm1.1(KOMP)Mbp
Targeted Allele Detail
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Symbol: |
Setd6tm1.1(KOMP)Mbp |
Name: |
SET domain containing 6; targeted mutation 1.1, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:5446143 |
Gene: |
Setd6 Location: Chr8:96442509-96445638 bp, + strand Genetic Position: Chr8, 47.17 cM, cytoband E2
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Alliance: |
Setd6tm1.1(KOMP)Mbp page
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IMPC: |
Setd6 gene page |
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Mutant Cell Lines: |
DEPD00513_4_C01, DEPD00513_4_D01 |
Germline Transmission: |
Earliest citation of germline transmission:
J:188991
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 2021 starting at position 96442973 and ending at position 96444994 of Chromosome 8 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Subsequent cre expression excised this neomycin resistance cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
(J:148605, J:173534, J:188991)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
6 reference(s) |
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