b2b773Clo
Chemically induced Allele Detail

Summary

• Symbol: b2b773Clo
• Name: Mutant line 773; Bench to Bassinet Program (B2B/CVDC), mutation 773 Cecilia Lo
• MGI ID: MGI:5446154
• Synonyms: Dasher
• Gene: b2b773Clo Location: unknown
• Alliance: b2b773Clo page

Mutant 773-002-NA exhibits TGA

Show the 8 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: B2B/CvDC

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. Additional incidental mutations were detected in sequencing for the causative mutation, b2b773Clo, and may be present in stocks carrying this mutation.

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any b2b773Clo Mutation: 1 strain or line available

Notes

Summative Diagnosis:
Cardiac Phenotype: Aortic valve dysplasia, transposition of the great arteries (TGA), coronary fistula

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID	Code Description
0700	D-loop transposition of the great arteries
1400	Aortic valve abnormality
2233	Coronary-cameral fistula to right ventricle

References

• Original: J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12
• All: 2 reference(s)